Manjiro Sano/Relationships

Takemichi Hanagaki
Mikey never met Takemichi in the past. They only meet by chance when Takemichi time leaps to the past, during which Takemichi challenges Masataka Kiyomizu from Kiyomasa's Gang to a 1v1. Noting Takemichi's bravery, he takes an interest in him by saying that Takemichi will be his "bitch" from now on. Later on, they become very close friends. Mikey has remarked that Takemichi is reminiscent of his deceased brother, who, even though his fighting prowess was mediocre, was valiant in battle and was an excellent leader.

Over time, Mikey comes to rely on Takemichi emotionally. He is the light that ensures Mikey will not fall to the darkness. Indeed, in one of the altered present timelines, Takemichi, for reasons unknown, had left Toman, which devastates Mikey, resulting in his fall to the darkness. He kills all his friends and becomes one of the present's most wanted criminals. Even so, the sliver of good left in Mikey at that point still desires for Takemichi's support, shown by the note slipped onto Takemichi's table in the present timeline that reveals his location. Mikey understands his sins and wants Takemichi to be the one to grant him peace at last. Without Takemichi, Mikey's descent into evil is inevitable.

Ken Ryuguji
Mikey and Draken are best friends. Mikey affectionately dubs Draken "Kenchin". They've known each other since 5th grade. At the time, Mikey had already made a name for himself as a fearsome fighter while Draken was a gopher for some older kids. Mikey encountered Draken when he was tasked to retrieve Mikey upon the older kids' orders. Mikey gets a good first impression of Draken and agrees to go with him to see the older kids. Mikey then easily knocks out the leader off those kids and invites Draken to be friends with him, to which the latter agrees happily. From then on, those two became inseparable.

The two have been shown to get into many pointless arguments, but always make up. Mikey is the more fun-loving of the two, while Draken is the more realistic individual. When Pah-chin gets arrested, Draken is able to reason, albeit with the help and intervention of Takemichi, with Mikey about Pah-chin's sacrificial yet correct choice.

The two are extremely close. The only time Mikey is shown crying in the series is for Draken when he is on the brink of death.

Keisuke Baji
Baji is Mikey's oldest friend. They had known each other since they were younger and even trained at the same dojo which is owned by Mikey’s grandfather. The two often joked around, even coming up with foreign names together to copy Emma’s.

Mikey cares for Baji deeply to the point of punching Hanemiya Kazutora to death after he killed Baji in an alternate timeline. Mikey is also shown to be crying when Baji passed during the conflict with Valhalla.

Shinichiro Sano
Shinichiro is Mikey's older brother. He was many years older than Emma and Mikey so he often took care of them. Shinichiro was Mikey's hero and looked up to him as he was the founded of the strongest fang at the time alongside a respected leader.

When Shinichiro died part of Mikey broke; and strived to continue his legacy. His deceased elder brother inspired him in many ways during his teen and adult years leading him and so many around him to greatness in their respected areas.

Emma Sano
Emma and Mikey are half siblings really close in age. Emma came to live with the Sano's at age 3 and they became close. Mikey is protective of his sister and has a soft spot for her. They're very close to the point the unsuspecting eye would think they were dating.

After her death he told her it was all wrong and it wasn't the life he thought she would get granted. Another part of his heart died with her.

Izana Kurokawa
Izana is Mikey's older adopted brother. Izana disliked Mikey for Shin would always talk about him to him. Izana wasn't raised with the Sano's he was Emma's biological mothers, husbands affair and when he found out he wasn't a Sano he broke. Shin wanted Izana to become family with Mikey and Emma and live the free life. Mikey wished to set Izana free from his loneliness but instead he died before getting the chance at the fight against Teijku. His last sibling to fall it lead to him being broken.